Platelet-Lymphocyte Ratio and Neutrophil-Lymphocyte Ratio as Early Mortality Predictors for Patients with End-Stage Chronic Liver Disease

Background: Chronic liver disease (CLD) often results in fatal complications. Child-Turcotte-Pugh (CTP) score is the earliest predictor of mortality but Model for End-Stage Liver Disease (MELD) more objective. Studies showed platelet-lymphocyte ratio (PLR) and neutrophil-lymphocyte (NLR) could become predictors chronic disease. We aimed to investigate NLR PLR as early CLD, comparison with CTP MELD scores. Method: This was a retrospective observational cohort study. recruited patients CLD (liver cirrhosis hepatocellular carcinoma), from Saiful Anwar Hospital, Indonesia. Data regarding PLR, NLR, CTP, scores were obtained medical records. Participants followed 30 days determine survival. Results: Ninety There 31 deaths (34.4%) days. Mortality higher HCC than cirrhosis. Although had similar sensitivity (51.6%), neither (p 0.956) nor 0.087) significantly better predict 0.001) or 0.002). In opposite positive correlation Conclusion: On contrary positively correlated severity disease, potential compared But not substitute both